WHAT IS COLEUS FORSKOHLII RHIZOME EXTRACT?
Coleus forskohlii rhizome extract, also known as Plectranthus barbatus (a taxonomic synonym), holds a significant place in traditional medicine globally, particularly within Ayurvedic practices. Belonging to the same botanical family as mint and lavender, it has been utilized as a medicinal herb in India for centuries.
Traditionally, this extract has been valued for supporting gastrointestinal, liver, respiratory, cardiovascular, and nervous system health. The active compound forskolin, sometimes referred to as coleonol, is uniquely derived from the roots of the C. forskohlii plant.
Coleus forskohlii root extract powder works by activating the adenylate cyclase enzyme, which elevates cyclic adenosine monophosphate (cAMP) levels. As a crucial cellular messenger, cAMP plays a role in multiple signaling pathways and physiological functions.
BASIC INFORMATION:
- Product Name: Coleus Forskohlii Root Extract 10% 20% Forskolin
- Latin Name: Coleus forskohlii (Willd.) Briq.
- Active Ingredient: Forskolin
- Molecular Formula: C22H34O7
- Molecular Mass: 410.501
- CAS No.: 66428-89-5
- Specification: 10%-20% (featured: 20%)
- Appearance: Yellow-Brown Fine Powder
COLEUS FORSKOHLII RHIZOME EXTRACT BENEFITS:
Forskolin’s ability to dilate blood vessels via cellular modulation may contribute to lowering blood pressure. While preliminary, further human studies are needed to confirm this effect.
May Support Glaucoma Prevention
Eye drops formulated with forskolin might aid in managing glaucoma, a condition linked to elevated intraocular pressure. An Italian study from 2013 observed that a combination of Coleus forskohlii rhizome extract and the flavonoid rutin reduced intraocular pressure by 10% in glaucoma patients after 30 days. Higher doses yielded more pronounced results.Potential to Reduce Intraocular Pressure
Research in India demonstrated that 1% forskolin-containing eye drops lowered intraocular pressure in adults with open-angle glaucoma over four weeks. The study involved 90 participants aged 18–60, who applied drops three times daily. Forskolin’s mechanism, linked to increased cyclic AMP levels—similar to certain asthma therapies—led to measurable pressure reduction at each follow-up visit.Asthma Risk Reduction
Elevated cyclic AMP levels from forskolin may relax airway muscles, mitigating respiratory spasms associated with asthma. A 2019 review cited a trial where daily intake of 10 mg forskolin capsules for six months improved asthma control in patients, paralleling effects of the medication sodium cromoglycate.Weight Management Support
Some studies suggest Coleus forskohlii extract may assist in weight loss, though current human data remains limited. Earlier trials from 2005 and 2007 indicated potential benefits, but additional research is necessary to validate these findings.Insulin Resistance Improvement
A randomized, double-blind, placebo-controlled study explored the impact of Coleus forskohlii root extract on metabolic health in overweight individuals. Participants receiving 250 mg of the extract daily for 12 weeks showed promising metabolic changes, though further investigation is required to solidify these results.
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